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Cognitive impairment in multiple system atrophy : changing concepts / ABRAHAO, Agessandro ; [et al].
Dementia & neuropsychologia, 2011, vol. 5 (4), p. 303-309.

http://www.demneuropsy.com.br/imageBank/PDF/v5n4a08.pdf... (11-06-2012)

Mots-clés principaux
:
Atrophie multisystémique
Trouble cognitif
Démence
syndrome parkinsonien


Résumé :

Multiple system atrophy (MSA) is characterized by a variable combination of cerebellar ataxia, parkinsonism and pyramidal signs associated with autonomic failure. Classically, cognitive impairment was not considered a clinical feature of MSA and dementia was pointed out as an exclusion diagnostic criteria. Based on comprehensive neuropsychological assessment, cognitive impairment was found to be a frequent feature in MSA, and clinically-defined dementia is now reported in 14-16% of cases. This article reviews the current data on cognitive impairment in MSA along with its neuropsychological profile and pathophysiology.

Langue : Anglais
Doc n° : 29737
NumRec : 6316503
 

       

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